Go to Serpents' Lair in Holy Innocents' Cemetery to challenge Medusa. Keep your back turned during the gaze; turn around and counterattack only after it ends.
Watch the wind-up first, then choose your response; the steps below are not a fixed attack sequence.
Detailed steps
Go to Serpents' Lair in Holy Innocents' Cemetery. You do not need to obtain Joan’s Infernal Pyre first to claim this battle’s rewards.
Gaze cycle: Turn your back to the main body to avoid petrification
Attacks: After raising its head, it unleashes Petrifying Gaze. Petrification also checks whether Rose is facing Medusa; this move ignores normal dodge and parry checks.
How to dodge: As soon as you see the gaze windup, stop attacking, turn your back to Medusa, and keep it turned until this gaze phase ends. Simply moving backward while still facing the main body is not enough; do not try to force through the gaze with a dash or parry either.
When to counter: Only after the gaze ends and recovery begins should you turn around, approach, and make a brief attack; keep watching the tail and melee windups; do not turn back early just to squeeze in another hit.
Attacks: The tail attack sweeps across the arena, after which multiple waves of rocks may fall in succession.
How to dodge: First move out of the tail's path, then watch overhead and the landing spots on the ground; the first rock landing does not mean the whole phase is over.
When to counter: Attack when both the tail attack and falling rocks have ended and the approach is safe; do not charge attacks while rocks are still falling overhead.
Complete the post-battle story sequence and absorb the reward orb to obtain Petrifying Gaze and The Prophetess's Key; then open the weapon chest that appears to claim Rusted Harpè and Aegis.
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The Prophetess's Key
Petrifying Gaze
Rusted Harpè and Aegis